As you can see, we have three main priorities to work on:
Clinical characterization/common CRF: Global COVID-19 Clinical Data Platform, COVID-19 observational cohort studies. Encourage member states to submit clinical anonymized data to our Global Platform. Email EDCARN@who.int for log-in information. Open. Weekly reports.
Modify CRF: make module with bare minimum variables, for ease of use in resource limited settings; add pregnancy related components. Deadline one week.
Encourage clinical researchers to conduct observational cohort studies--use ISARIC CCP for biological sampling to understand transmission. Ongoing
Core clinical outcome set for clinical trials: Delphi process to produce set-be prepared to fill out survey shortly. Deadline one week.
Interventional studies:High flow oxygen: evaluate extent of aerosol production (IPC)-protocol in development. Deadline two weeks.
Steroids and COVID-19 disease: review REMAP-CAP study protocol (see link below). Systematic review commissioned. Deadline one week to review trial protocol, to be discussed at next TC.
Develop optimized supportive care protocol. Deadline 3 weeks.
Our working group governance (in development) but includes:
Co chairs: John and Srin will continue. YaeJean to support back up as needed.
Group members: agree to participate in group and contribute scientifically. If you do not desire to participate please let me know. All have signed confidentiality agreements.
New members: Add methodologist to the panel and ensure adequate regional representation. Increase representation from China.
Weekly TCs to discuss scientific issues, and move forward the agenda.